In 2002, she and her husband developed the series Watching Ellie, which lasted two seasons. in 2006, she was cast as Christine Campbell in the sitcom The New Adventures of Old Christine, which lasted for five seasons on CBS. Her mother, Judith was a writer and special needs tutor, and her father, Gérard Louis-Dreyfus (also known as William Louis-Dreyfus), was a French attorney and business executive. During her time on SNL she appeared alongside several actors who would later rise to prominence, such as Eddie Murphy, Jim Belushi, Billy Crystal and Martin Short. More recently Louis-Dreyfus has commented that her casting on SNL was a “Cinderella-getting-to-go-to-the-ball kind of experience”, however, she has also admitted that at times it was often quite tense, stating that she “didn’t know how to navigate the waters of show business in general and specifically doing a live sketch-comedy show.” Following her 1985 departure from SNL, Louis-Dreyfus appeared in several films, including Hannah and Her Sisters which was directed by Woody Allen, and the cult classic National Lampoon’s Christmas Vacation in which she starred alongside Chevy Chase. The series and its concept was created by writer and producer of Will & Grace, Kari Lizer. The series told the story of Christine Campbell, a single mother who manages to maintain a fantastic relationship with her ex-husband, while running a women’s gym. The series debuted on CBS in March 2006 to an audience of 15 million and was initially a ratings winner for the network.

She was later cast in the role of Elaine Benes on the NBC sitcom Seinfeld for which she achieved much critical and commercial success. She has a total of twelve Emmy Award nominations – seven for supporting actress in a comedy series for Seinfeld, and five for lead actress in a comedy series for The New Adventures of Old Christine. in May 2010, Louis-Dreyfus received a star on the Hollywood Walk of Fame for her contribution to the broadcast television industry. Only a year after her birth, her parents divorced in 1962. Louis-Dreyfus has two half-sisters on her father’s side, Emma and Phoebe.

In 2002, she and her husband developed the series Watching Ellie, which lasted two seasons. Both her paternal grandmother and mother were American. Through her father, a billionaire heir to the Louis Dreyfus Group, one of the world’s largest commodities trading and merchandising firms, she had a cousin, Robert Louis-Dreyfus (1946-2009), former CEO of Adidas and owner of the Olympique de Marseille soccer team.

She rose to prominence as one of the regular cast members of Saturday Night Live in the early 1980s. Throughout her career she has received two Emmy Awards, a Golden Globe Award and five Screen Actors Guild Awards. She has a total of twelve Emmy Award nominations – seven for supporting actress in a comedy series for Seinfeld, and five for lead actress in a comedy series for The New Adventures of Old Christine.

In 2002, she and her husband developed the series Watching Ellie, which only lasted two short seasons. in 2006, she tried her luck one again playing the titular role of Christine Campbell in the sitcom The New Adventures of Old Christine, which lasted for five seasons on CBS. Her parents divorced in 1962, a year after her birth.